摘要
未成熟心肌与成熟心肌在结构、功能、能量代谢及对缺血、缺氧的耐受性方面差别明显。目前尽管可以成功地矫正先天性心脏缺陷,但是其术中不适当的心肌保护所造成的低氧血症、心肌功能障碍却是导致患儿术后死亡的重要原因。所以,寻求一种与未成熟心肌生理、功能等相适应的心肌保护措施,一直是小儿心脏外科共同关注的焦点,近年来出现的各种停跳液的灌注方法,为婴幼儿的心肌保护提供了新的思路。
There are significant differences in the structure, function, energy metabolism and isehemia, hypoxia tolerance between immature myocardium and mature myocardium. At present, in spite of the successful use of surgical correction for congenital heart defects, the hypoxemia, myocardial dysfunction caused by inappropriate myocardial protection is an important reason for postoperative patients death. Therefore,the search for protective measures which is fit for physiology and function of immature myocardium has been a common focus of attention for cardiac surgery in children. In recent years,various methods of cardioplegia perfusion provide a new way of thinking for myocardial protection of infants, and young children.
出处
《医学综述》
2010年第1期82-84,共3页
Medical Recapitulate
关键词
心肌保护
未成熟心肌
单次灌注
多次灌注
体外循环
Myocardial protection
Immature myocardium
Single dose
Multiple dose
Extracorporeal circulation
