摘要
目的:研究近红外光谱技术在新生儿缺氧缺血性脑病(Hypoxic ischemic encephalopathy,HIE)脑氧饱和度(regional oxygen saturation,rSO2)检测的临床应用价值。方法:收集我院2006年至2009年HIE患儿70例(包括轻度HIE组46例及中、重度HIE组24例),同时收集产科同期的足月健康儿30例作为对照组,分别在12h、24 h、72 h用近红外光谱检测技术(near infrared spectroscopy,NIRS)测定安静状态下的rSO2,并使用脉搏血氧仪监测SpO2,进行组间比较。结果:NIRS数据显示3组不同时间rSO2组间差异有显著统计学意义(P<0.05),在轻型HIE组,各时间的rSO2差异有统计学差异(P<0.05);而SpO2监测分析,中、重度HIE组,轻度HIE组与对照组之间差异无统计学意义(p>0.05)。结论:在新生儿HIE时,NIRS能准确监测rSO2,客观评价脑组织的氧合状态,为评价HIE患儿脑损伤程度提供客观、量化的依据。
Objective： To study the clinical application of near infrared spectroscopy in detecting regional oxygen saturation （ rSO2 ） in neonatal hypoxic ischemic encephalopathy （ HIE ）. Method： Collected 70 cases of neonatal with HIE from 2006 to 2009 in our hospital （ including mild HIE group 46 cases and the moderate and severe HIE group 24 cases） and 30 cases of full - term healthy infants as control group at Obstetrics, the rSO2 was detected using near infrared spectroscopy （ NIRS） at 12h, 24 h, 72 h respectively. While the the SpO2 was detected by using the pulse oximeter for monitoring. Result： NIRS data showed rSO2 of three groups at different time had significant difference between them （ P 〈 0.05 ）. In mild HIE group, rSO2 of each time had statistically significant difference （ P 〈 0.05 ） ; and SpO2 data showed moderate and severe HIE group and mild HIE group and control group were no statistically significant difference between them （ P 〉 0.05 ）. Conclusion： In HIE infants, NIRS can monitor the rSO2 accurately, evaluate brain tissue oxygenation status objectively, provide an objective and quantitative basis.
出处
《河北医学》
CAS
2010年第1期6-8,共3页
Hebei Medicine
基金
广东省医学科学技术研究基金(粤卫【2006】129号文下达的科研项目
编号:A2006649)
