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类风湿关节炎的生物治疗进展 被引量:5

Progress of biological agents for rheumatoid arthritis
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摘要 类风湿关节炎(RA)是常见的系统性自身免疫性疾病,致残率高,严重影响患者健康。随着基因和生物技术的进步,发现多种RA治疗靶点,相关生物制剂的开发是近期研究的热点。本文主要综述近年用于RA治疗的生物药物的研究进展,包括针对细胞因子、免疫细胞和信号转导过程各种酶的药物。 Rheumatoid arthritis (RA) is the most common systematic autoimmune disease with considerable morbidity and mortality. This review summarizes the biological therapeutics developed for RA mainly focuses on several targets including cytokines, immune cells and enzymes, which regulate signal transduction process.
出处 《世界临床药物》 CAS 2010年第1期40-43,共4页 World Clinical Drug
基金 国家高技术研究发展计划(863计划)项目
关键词 类风湿关节炎 生物治疗 细胞因子 免疫细胞 酶抑制剂 rheumatoid arthritis biological agent cytokine immune cell enzyme inhibitor
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参考文献10

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