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843例儿童急性呼吸道感染血清IgM测定与分析 被引量:22

Detection and analysis of serum IgM in children with acute respiratory tract infection
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摘要 目的对儿童常见呼吸道感染病原体作统计分析并了解其流行趋势。方法采用ELISA法对843例急性呼吸道感染(ARI)患儿血清中的IgM抗体进行测定后,按性别、年龄、发病季节分组后进行统计分析。结果286人次IgM测定阳性,总阳性率33.9%;以呼吸道合胞病毒(RSV)检出率最高(38.1%),其在性别组、季节组间差异无统计学意义;在年龄组(尤其是小于3岁以下组)间差异有统计学意义。肺炎支原体(34.3%)、肺炎衣原体(11.5%)在年龄组和季节组中差异有统计学意义。结论RSV、肺炎支原体为衡阳地区儿童ARI常见病原体,RSV为新生儿常见病原体,肺炎支原体、肺炎衣原体感染多见于3岁以上儿童,流行于冬春季。 Objective To explore the epidemic tendency from the etiology of the children with acute respiratory tract infection. Methods Serum specific lgM antibody were measured by ELISE in 843 children with acute respiratory tract infection. To perform statistical comparison of the data collected from the groups according to sex,age and epidemic season. Results 286 case times were IgM antibody positive (total positive rate 33.9%) and the positive rate of RSV was the highest (38. 1%) ,in which the age group (especially in age 〈 years) had statistical difference. The positive rate of mycoplasma pneumoniae(MP,34. 3%) and chlamyclophila pneurnonitractate(Cpn,11.5%) had statistical difference between the age group and epidemic season group. Conclusion MP is the common pathogen in our regional children with acute respiratory tract infection. RSV often infects the newborn baby. Children above 3 years frequently infected with MP and Cpn,which are dominant the first and the fourth season in one year.
作者 吴华
出处 《检验医学与临床》 CAS 2010年第1期25-26,共2页 Laboratory Medicine and Clinic
关键词 急性呼吸道感染 呼吸道合胞病毒 抗体.病毒 免疫球蛋白M 儿童 acute respiratory tract infection respiratory syncytial virus antibodies,viral immunoglobulin M child
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