摘要
为了考察磷酸钠口服清肠液(Ⅰ号)进行肠道准备的效果及安全性,选择了1995年6月至1996年3月间门诊及住院病人需作大肠镜检查者108例,以传统的口服洗肠液(Ⅱ号)为对照,随机分组,盲法给药,通过问卷调查对二者的耐受性、味道、不良反应及清洁效果等进行对比。结果显示Ⅰ号与Ⅱ号相比,患者可接受率分别为87.5%与69.2%,乐于饮用者分别为32.2%与15.4%,差异有显著性(P<0.05)。提示前者易于耐受,味道较好,因此,清肠效果必然满意。末发现严重不良反应及血化学改变,血渗透压改变在正常范围内,说明Ⅰ号液为一有效而安全的口服清肠剂。
For investigating the effectiveness and safety of oral sodium phosphate in preparation for colonoscopy,108 cases from both outpatient and inpatient clinics from June,1995 to March,1996 were randomized and blinded to receive either oral sodium phosphate or standardized electrolyte lavage solu- tion as control.The questionaire was designed for scoring by patients and doctors regarding to its toler- ance,taste,side effects and cleaning degree etc.Results showed that the tolerance rates in oral sodium phosphate and electrolyle lavage were 87.5% and 69.2% and the rates of preference in using them were 32.2% and 15.4% respectively(P<0.05),implying a better tolerance and taste in favor of the for- mer.Only a few side effects and little biochemical and osmotic changes were noticed.It is indicated that oral sodium phosphate is an effective and safe intestinal cleaning agent for colonoscopic preparation.
出处
《中华消化内镜杂志》
1998年第5期278-280,共3页
Chinese Journal of Digestive Endoscopy
