摘要
目的观察与评估在冠状动脉造影和介入治疗术后即刻在股动脉穿刺处使用Angio-Seal血管封堵器的安全性与并发症发生率。方法选择2007年以来257例经股动脉途径进行冠状动脉造影和介入治疗术后的患者。A组108例符合入选标准者使用Angio-Seal血管封堵器;B组149例病人使用徒手压迫止血。结果本资料A组即刻均成功,无一例操作失败,但发生迟发腹股沟较大血肿4例,腹膜后血肿1例,假性动脉瘤1例,迟发出血并发症5.6%,总体出血并发症5.6%。B组即刻失败5例,形成腹股沟血肿及大片状淤血,假性动脉瘤1例,迟发出血并发症0.7%,总体出血并发症4.0%,迷走反射8例。结论使用Angio-Seal血管封堵器可以快速、有效止血,减少卧床时间及卧床造成的不适度。但由于存在一定的并发症,在临床使用时,应严格掌握指征、选择合适的患者。
Objective To observe and evaluate the safety and complication rate of Angio-Seal closure device for systematic sealing of femoral access sites after coronary diagnostic angiography and percutaneous coronary intervention. Methods Total 257 patients were divided into Angio-Seal closure group （group A, n=108） and manual compression group （group B,n=149） after diagnostic angiography and percutaneous coronary intervention. The primary safety endpoint was the incidence of major complications during the in-hospital period. Results Compared with group B,the Angio-Seal closure device offered rapid and reliable hemostasis and less vasovagal reflex （P〈0.05）. But there was no significant difference in the total success rate of hemostasis which contributed to groin bematoma in group A. There was no differerce in the incidence rate of retroperitoneal and pseudo-aneurysm between group A and group B. Conclusion Systematic sealing of femoral access sites after angiographic and interventional procedures with Angio-Seal closure device can offer rapid and reliable hemostasis and reduce bed rest time and discomfort. But Angio-Seal closure device can induce complications and in clinical use,we should strictly control indications and select the appropriate patients.
出处
《中国现代医生》
2009年第36期33-34,36,共3页
China Modern Doctor
