摘要
目的总结胰十二指肠切除术后早期的主要并发症并分析其可能原因。方法回顾性分析1990年2月—2009年5月因壶腹部恶性肿瘤实施的576例胰十二指肠切除术后患者的临床资料。结果术后85例(14.8%)患者发生早期并发症92例次,其中以胃肠道功能障碍、胰漏、腹腔感染以及术后出血最多见;围手术期死亡7例(病死率1.22%),其中3例死于多系统器官功能衰竭,2例死于失血性休克,2例死于感染性休克。危险因素分析显示,术前低蛋白、高胆红素血症与术后高并发症发生率相关。结论术前细致准备,术中精细操作,术后加强观察,是降低术后早期并发症,改善PD术后患者预后的关键。
Objective To summarize the main early complications after pancreatoduodenectomy and analysis of the probable causes.Methods The clinical data of 576 cases who underwent pancreatoduodenectomy(PD) in our department between Feb 1990 and May 2009 were analysed retrospectively.Results There were 92 early postoperative complications occurred in 85 patients(14.8%).Gastrointestinal dysfunction,pancreatic leakage,intra-abdominal infections and hemorrhage were the most of complications,and 7 cases died during perioperative period(mortality 1.22%),among which 3 died of multiple system organ failure,2 died of hemorrhagic shock and 2 died of toxic shock.Preoperative hypoproteinemia and hyperbilirubinemia complicated with a high incidence of postoperative complications on multivariate analysis.Conclusions Meticulous preoperative preparation,delicate intraoperative technigne and close postoperative observation are the key points to decrease early complications and improve the prognosis of the patients who undergo PD.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2009年第12期1284-1287,共4页
China Journal of General Surgery
关键词
胰十二指肠切除
手术后并发症
回顾性研究
Pancreaticoduodenectomy
Postoperative Complications
Retrospective Studies