摘要
目的对米非司酮配伍米索前列醇用于稽留流产的临床疗效进行荟萃分析。方法计算机检索PubMed、EMBASE数据库、EBSCOhost数据库及中国期刊全文数据库、中国优秀博士学位论文全文数据库、中国优秀硕士学位论文全文数据库、中国重要会议论文全文数据库、维普中文科技期刊数据库、中国生物医学文献数据库(cBMdisc)、万方数据库所有对比米非司酮配伍米索前列醇与雌激素用于稽留流产的临床随机对照试验,进行质量评价后用RevMan4.2软件进行荟萃分析,主要分析完全流产率及二次清宫率。结果共纳入9个随机对照试验,Meta分析结果显示:米非司酮配伍米索前列醇组与雌激素组在完全流产率和二次清宫率上的差异均有统计学意义。完全流产率米非司酮配伍米索前列醇组显著高于雌激素组,而二次清宫率显著低于雌激素组。结论米非司酮配伍米索前列醇可以用于稽留流产。
Objective To make a meta - analysis of the clinical therapeutic effect of mifepristone add misoprostol used in missed abortion. Methods Literature search was conducted for all randomized controlled trials （RCTs） between 1980 and 2009, which compared mifepristone add misoprostol and estrogens used in missed abortion. Using the Revman4.2 to make a meta - analysis. Results There are 9 clinical randomized controlled trials. Meta - analysis indicated that there are statistical differences in complete abortion rate and second operation rate between mifepristone add misoprostol and estrogens. Conclusion Mifepristone add misoprostol can be used in missed abortion.
出处
《海南医学》
CAS
2010年第1期54-56,共3页
Hainan Medical Journal
