摘要
目的:探讨胃肠道间质瘤(GIST)的多层螺旋CT征象与恶性分级的相关性。方法:回顾性分析64例胃肠道间质瘤的资料,所有病例均行多层螺旋CT平扫及增强扫描,并经病理免疫组织化学检查证实。结果:间质瘤以胃部多见,占62.50%(40/64),其次为小肠,占18.75%(12/64)。GIST多表现为类圆形实性,边界清楚(47/64),以外生性生长为主(32/64)。密度多不均匀,坏死(47/64)、溃疡(31/64)常见,以不均匀强化、延迟强化为主。肝脏和腹腔为主要转移部位,转移灶坏死常见,也呈延迟强化。11例GIST伴发其他肿瘤。GIST的部位、坏死与溃疡的存在、强化方式及转移灶的有无与恶性分级呈正相关(P<0.05)。结论:胃肠道间质瘤的螺旋CT表现具有一定特征,并且不均匀强化方式,CT图像上坏死与溃疡的检出、转移灶的出现以及发生部位有助于对恶性间质瘤的判定。
Objective: To discuss the sign of gastrointestinal stromal tumors(GISTs)in spiral CT and to a- nalysis its malignancy grade. Methods: Sixty-four cases of GISTs were analyzed retrospectively, all were checked by multi- slice spiral CT plain and enhancement scanning, and had immunity histochemistry con- firmation. Results: The tumors were more in the stomach (40/64), the stomach body (n = 16) and the fundus (n = 11), and then in intestine (12/64). Most GIST were heterogeneous solid mass with clear boundary (47/64), exophytic growth (32/64), and always had necrosis (47/64) and ulcer (31/64), which had nonuniform strengthen, especially in delayed enhancement. Liver (11/13) and peritoneal (5/13) were the more likely metastatic sites. 11 cases were accompanied with other tumors. GIST size, with necrosis and ulcer, non-uniform strengthen and had metastatic location had positive relationship with malignancyo(P 〈0.05). Conclusion: GIST has some characteristic findings in Spiral CT. Some CT features maybe helpful in analysis of GIST malignancy grade.
出处
《新疆医科大学学报》
CAS
2009年第12期1728-1731,共4页
Journal of Xinjiang Medical University
关键词
胃肠道间质瘤
X线计算机
恶性分级
gastrointestinal stromal tumors
X-ray computed
malignancy grade