期刊文献+

恶性肿瘤药敏试验方法研究进展 被引量:4

The Progress of Malignant Tumor Drug Sensitivity Test Methods
下载PDF
导出
摘要 恶性肿瘤是严重危害人类生命和健康的常见病和多发病,其病死率居各类疾病之首,化疗是恶性肿瘤的主要治疗手段之一。个体化治疗已成为化疗的趋势,肿瘤药敏试验可指导临床用药进行个体化治疗。本文综述了多种肿瘤药敏试验方法的原理、方法、优缺点及其目前在恶性肿瘤化疗中的应用和面临的问题。 Malignant tumor is a commonly and frequently encountered disease that causes serious damage to human health. Its mortality rate is the first one among all kinds of the diseases. Chemotherapy is the one of main therapy for malignant tumor. Individual treatment has become tendency of chemotherapy. Drugs sensitivity experiment of cancer is a guidance for clinical medication and individual treatment. This paper describes the principle, method and advantages and disadvantages of many drugs sensitivity experiments of caneer. Also,the application of chemotherapy and facing problems of this experiment will be discussed in this review.
出处 《医学综述》 2009年第24期3702-3706,共5页 Medical Recapitulate
关键词 恶性肿瘤 抗癌药物 药敏试验 Malignant tumor Anticancer drug Drugs sensitivity experiment
  • 相关文献

参考文献30

  • 1Fibig HH, Schuchhardt C, Henss H,et al. Comparison of tumor response in nude mice and in the patients [ J ]. Behring Inst Mitt, t 984,174 ( 74 ) : 343-352. 被引量:1
  • 2Kuo TH, Kubota T, Watanabe M ,et al. Site-specific chemosensitivity of human small-cell lung carcinoma gtowing orthotopically compared to subcutaneously in SCID mice:the importance of orthotopic models to obtain relevant drug evaluation deta [ J ]. Anticancer Res, 1993,13 (3) :627-630. 被引量:1
  • 3卢绍平,董玉宁,戚和玲,唐小兰,樊安银,陈建超,任光国,陈利华,饶建章,勾厚义,黄金顶,唐令超,陈江凯,汪昌美,温玉明.肾包膜下接种法预测人体肿瘤化疗敏感性的可行性探讨[J].中国肿瘤临床,1994,21(7):546-549. 被引量:1
  • 4孙京栋,梁澍,李静,李相林,王正琪,史长青,吕梅菊.正交设计在SRCA肿瘤药敏测定中应用的临床研究[J].中国肿瘤临床,1997,24(12):885-889. 被引量:2
  • 5樊亚群 黎之楣 魏立勇 等.急性非淋巴细胞白血病体外药敏试验--集落形成法与-^3H-TdR掺人法的初步研究.福建医药杂志,1994,16(3):105-106. 被引量:1
  • 6Mori T, Ohuishi M, Komiyama M ,et al. Prediction of cell kill kinetics of anticancer agents using the collagen gel droplet embedded- culture drug sensitivity test [ J ]. Oncol Rep,2002,9 ( 2 ) : 301-305. 被引量:1
  • 7Funa K, Dawson N, Jewett PB,et al. Automated fluorescent analysis for drug-induced eytotoxicity assays [ J ]. Cancer Treat Rep, 1986, 70(10) :1147-1151. 被引量:1
  • 8Csoka K, Larsson R, Tholander B, et al. Cytotoxic drug sensitivity testingof tumor cells from patients with ovarian carcinoma using the fluorometri microcuhure cytotoxicity assay ( FMCA ) [ J ]. Gynecol Oncol, 1994,54 ( 2 ) : 163-170. 被引量:1
  • 9Mosmann T. Rapid colorimetric assay for cellulair growth and sur- vival:application to proliferation and cytotxicity assays[ J]. lmmunol Methods, 1983,65 ( 1/2 ) :55-63. 被引量:1
  • 10于翠珍,李双标,李胜水,张凤梅,刘岩.卵巢癌细胞MTT法对化疗药物敏感性的研究[J].中国医药导报,2009,6(2):11-12. 被引量:3

二级参考文献65

共引文献85

同被引文献43

引证文献4

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部