摘要
青霉素裂解液在结晶６ＡＰＡ后，仍残留有０３％（Ｗ／Ｖ）６ＡＰＡ，生产厂每天约有１５吨６ＡＰＡ结晶母液，若能将母液中残余产品进行回收，每天可多得４０ｋｇ以上６ＡＰＡ，价值约在１９２００元以上，每年可得额外产值５７６万元以上（按３００ｄ计）。其...
Crystallization mother liquor usually containing about 0.3% of 6 aminopenicillanic acid(6 APA), was processed by reverse osmosis system (RO). 6 APA rejection factor to Nanomax 50 membrane (Millipore Co.LTD.) was above 99%. The salts contained in the mother liquor such as NH 4Cl, KCl can permeate the membrane. Three batches of typical RO experiments were carried out. 6 APA solution were concentrated 20～30 times at a yield of over 98%. The concentrated 6 APA solution was then crystallized with a yield of 83.5%～85.6% and purity of 97%. Another eight batches were repeated and the results were similar.
出处
《生物工程学报》
CAS
CSCD
北大核心
1998年第4期468-471,共4页
Chinese Journal of Biotechnology
关键词
青霉素裂解液
6-APA
回收
反渗透法
Reverse osmosis, 6 APA, crystallization mother liquor concentration, crystallization
