摘要
目的:回顾性分析临床常见病原菌类型及其对常用抗菌药物的耐药情况,为临床合理使用抗菌药物提供参考。方法:2007年1月-2007年12月,本院检出的876株病原菌类型及药敏试验结果进行分析。结果:临床送检的感染性疾病患者标本中分离病原菌的构成分别为:G-菌为63.15%(553/876)、G+菌为27.17%(238/876)、真菌为9.68%(85/876)。临床常见G-病原菌依次为:大肠埃希菌42.86%(237/553)、铜绿假单胞菌14.65%(81/553)、肺炎克雷伯菌12.30%(68/553)、不动杆菌属11.93%(66/553);G+病原菌依次为:表皮葡萄球菌51.86%(123/238)、金黄色葡萄球菌31.93%(76/238)。对抗菌药物耐药性检测结果显示:多数G-菌对亚胺培南、第3代头孢菌素敏感;G+菌对万古霉素敏感。结论:2007年病原菌仍以G-菌为主,以大肠杆菌最多,球菌中以表皮葡萄球菌最多,均对大部分常用抗菌药物耐药。
Objective： To provide the reference for clinical rational use of antibacterial drugs through the method of retrospective analysis the clinical drug resistance of common pathogens ＆ antibacterial agents. Methods： Analyzing 876 strains of pathogens detected and test results of antimicrobial susceptibility from January 2007 to December 2007. Results： The constitution of the clinical specimen pathogens separated from the infected patients included： 63.15%（553/876） were Gram-negative bacteria of 27.17%（238/876） were Gram-positive bacteria and 9.68%（85/876） were fungi. The constitution of the clinical common Gram-negative bacteria included： 42.86%（237/553） were Escherichacol, 14.65%（81/553） were Pseudomonas aerugionosa, 12.30%（68/553） were Klebsiella pneumoniae, 11.93%（66/553） were acinetobacter. The constitution of the clinical common Gram-positive bacteria included： 51.86%（123/238） were Staphylococcus epidermids, 31.93%（76/238） were Staphylococcus aureus. The test results of antimicrobial resistance were as follows： most of Gram-negative bacteria were sensitive to imipenem and the third generation of cephalosporin, and Gram-positive bacteria were sensitive to vancomycin. Conclusion： Gram-negative bacteria were as the main part of pathogens, E coli was in the majority; Staphylococcus epidermids occupied the most part of coccus and they were sensitive to most commonly used antimicrobial drugs.
出处
《抗感染药学》
2009年第4期268-270,共3页
Anti-infection Pharmacy
关键词
病原菌
抗菌药物
耐药性
pathogens
antibacterials
drug resistance
