摘要
目的调查住院病人糖尿病足（DF）和下肢动脉病变（PAD）的发病情况，分析两者之间的相关性。方法测定523例住院糖尿病病人空腹及餐后血糖、HbA1c、血脂分析和尿微量白蛋白浓度等。应用多普勒超声技术评估所有糖尿病住院病人PAD病情，检查股动脉、股浅动脉、胭动脉、胫前动脉、胫后动脉和腓动脉。根据检查结果分为3组：无病变组、轻度病变组（血管狭窄〈50％）和重度病变组（血管狭窄≥50％）。糖尿病足诊断按照Wagner标准。结果在因糖尿病住院523例病人中，DF95例（18．2％），PAD311例（59．5％），其中重度PAD131例（25．0％）。95例DF病人中重度PAD55例（57．9％）。Logistic回归分析显示，严重PAD（OR=5．00）是DF的独立危险因素。其他危险因素包括吸烟、高血压和糖尿病神经病变。结论严重PAD是DF最主要的危险因素。
Objective To investigate the prevalence of peripheral arterial occlusive disease （PAD） and diabetic foot among in-patients with diabetes ,and to analyze the relation between these two complications. Methods Five-hundred and twenty-three patients with type 2 diabetes were enrolled. Fasting and postprandial plasma glucose, HbA1c ,serum lipid profile and urinary albumin were determined. Femoral artery,profunda femoral artery, popliteal artery, anterior tibial artery, posterior tibial artery, and peroneal artery were checked by Doppler uhrasonography. The patients were then subdivided into groups with non-PAD ,mild PAD （artery stenosis 〈 50% ） and severe PAD （artery stenosis ≥ 50% ）. Diabetic foot was diagnosed using Wagner criterion. Results Among the 523 patients, 95 patients were afflicted with diabetic foot,311 patients with PAD in which 131 with severe PAD. As many as 55 severe PAD eases were found in diabetic foot patients. Multivariate logistic regression analysis revealed that severe PAD was significantly associated with diabetic foot （ OR = 5. 00 ）, other risk factors included smoking habit, hypertension and neuropathy. Conclusion Severe PAD seems to be the most important risk factor related to diabetic foot.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2009年第6期598-600,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病足
下肢血管病变
超声检查
多普勒
彩色
Diabetic foot
Peripheral arterial diseases
Uhrasonography, Doppler, color
