摘要
目的:观察右室不同部位起搏对心室重构和心功能的影响.方法:所选患者均植入人工双腔永久起搏器.据右室电极植入部位的不同分为右室心尖部起搏组和右室间隔部起搏组.常规彩超测定左室射血分数、心输出量、室间隔厚度;应用组织多普勒测量室间隔及左室基底段、心尖段的收缩达峰时间;BNP的变化.随访时间18个mo.结果:两组间比较,LVEF,CO无显著性差异(P≥0.05),室间隔厚度出现差异(P≤0.05).应用组织多普勒测量两组间不同节段的收缩达峰时间存在差异(P≤0.05).间隔部起搏组BNP低于右室心尖部起搏组,差异有统计学意义(P≤0.05).结论:长期心尖部起搏较易引起心室重构,BNP的升高,在观察过程中尚未发现心功能的下降.
AIM：To observe the effects of right ventricular pacing in different parts on left ventricular remodeling and cardiac function.METHODS：All of patients,implanted by dual-chamber pacemakers,were divided into 2 groups：RVA pacing group and RVS pacing group,according to the implanted right ventricular electrode position in the different parts.Patients were evaluated and compared for left ventricular ejection fraction,cardiac output,septal thickness,time to peak contraction in different parts and serum BNP level at 18 months follow-up period.RESULTS：At 18 months,there was no significant difference in left ventricular ejection fraction and cardiac output respectively,in comparison of RVOT and RVA implants（respectively P〉0.05）.However,the septal thickness shorted（P〈0.05） and the serum BNP level clearly decreased in the RVS group（respectively P〈0.05）.CONCLUSION：Long-term apical pacing could cause ventricular remodeling and elevation of the serum BNP level.However,the cardiac function decline has not yet found in the process of observation.
出处
《第四军医大学学报》
北大核心
2009年第23期2838-2840,共3页
Journal of the Fourth Military Medical University
关键词
右心室心
脏起搏
人工
心脏功能
脑钠肽
right ventricular
cardiac pacing
artificial
cardiac funtion
BNP
