摘要
目的 探讨利培酮对不同类型精神分裂症的临床疗效。方法 对符合ICD—10及CCMD—2—R诊断标准的偏执型、未定型、单纯型精神分裂症、精神分裂症残留期、精神分裂症衰退期共28例患者进行了8周开放性治疗;对3例难治性精神分裂症患者进行了12周的开放性治疗。利培酮剂量分别为4mg/日与6mg/日。疗效与副反应分别用PANSS及TESS量表评定。结果 精神分裂症偏执型、未定型、单纯型、残留期、衰退期以及难治性精神分裂症的减分率分别为85.38％、65.60％、51.33％、19.00％、0.00％、0.00％。结论 利培酮对精神分裂症偏执型疗效最好,未定型较好,对单纯型、残留期精神分裂症有一定疗效,对衰退期以及难治性精神分裂症疗效不明显。副反应比较轻微。
Objective To explore the clinical efficacy of risperidone in different type of schizophrenia. Methods 28 cases of different types of schizophrenic patients were treated with risperidone for 8 weeks, and 3 cases of drug-resistant schizophrenic patients were treated for 12 weeks. The efficacy and side effects were assessed with PANSS and TESS respectively. Besults The decrement rates of schizophrenics were paranoid type, 85. 38% ; undifferentiated type, 65. 60% ?simple type, 51. 33% ! residual stage, 19. 00% ; chronic deteriorated stage, 0% ; and drug-resistant case. 0%. Conclusions Risperidone has better efficacy in the treatment of paranoid and undifferentiated type schizophreni-a.
出处
《上海精神医学》
1998年第3期134-136,共3页
Shanghai Archives of Psychiatry
