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必需脂肪酸与银屑病关系的研究概况

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摘要 银屑病是一种慢性、易复发的炎症性皮肤病.临床特征是表皮银白色鳞屑、薄膜现象和血露(点状出血)现象^[1],严重影响患者的生活质量。必需脂肪酸(EFA)是人体自身不能合成,必需依赖食物供给的脂肪酸,属于多不饱和脂肪酸,包括亚油酸、亚麻酸和花生四烯酸(AA)^[2]。它在维持表皮细胞膜的结构和保证表皮组织的正常生长中起着重要的作用,表皮组织是EFA缺乏后首先受到影响的器官^[3],所以银屑病的发生与EFA之间有必然的联系,EFA缺乏可能是银屑病发生的原因之一。
出处 《中国现代医药杂志》 2009年第12期124-125,共2页 Modern Medicine Journal of China
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  • 1郑茂荣.关于银屑病治疗的几个问题[J].中华皮肤科杂志,1997,30(2):81-84. 被引量:21
  • 2Lewis R A, Austen K F, Soberman R J, et al. Leukotrienes and other products of the 5 -lipoxygenase pathway. New Engi J Med, 1990, 323(10) :645 -655. 被引量:1
  • 3Flynn D L, Capiris T, Cetenko W J, et al. Nonsteroildal anti-inflammatory drug hydroxamic acids, dual 5 -lipoxygenase and cyclooxygenase inhibitors. J Med Chem, 1990, 33:2070-2072. 被引量:1
  • 4Hidaka T, Hosoe Y. Pharmacological properties of a new anti-inflammatory compound, alpha-( 3, 5-di-tert-butyl-4-hydroxybenylidine )-gammabutyrolactone (KME..4), and its inhibitory effects on prostaglandin synthesase and 5 -lipoxyganaase. Jpn J Pharmacol, 1984, 36(1) :77 -85. 被引量:1
  • 5Lee S J, Frieson M R, Wong S, et al. BF-389. Drugs Fut, 1992, 7:12-14. 被引量:1
  • 6Ikuta H, Shirota H, Kobayashi Y, et al. Synthesis and anti-inflammatory activities of 3-(3,5-di-tert-butyl-4-hydroxybenzylidine) pyrrolidin-2-ones.J Med Chem, 1987, 30( 1 ): 1995 -2004. 被引量:1
  • 7Nagaki M, Tsuri T, Jyoyama H, et al. Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (γ-sultam) skeleton: cytokine suppressive dual inhibirors of cyclooxygenase-2 and 5-lipoxygenase. J Medl Chem,2000, 43: 2040 -3048. 被引量:1
  • 8Unangst P C, Connor D T, Cetenko W A, et al. Synthesis and biological evaluation of 5-[ [ 3,5-bis-( 1,1-dirnsthylethyl)-4-hydroxylphenyl ] methylene ] oxazoles, -thiazoles, -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with anti-inflammatory activity. J Med Chem,1994, 37(2) :322 -328. 被引量:1
  • 9Janusz J M, Young P A, Ridgeway J M, et al. New cyclooxygenase-2/5-Lipoxygenase inhibitors. 1. 7-tert-butyl-2,3-dihydro-3, 3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation of the 5-keto-substituent. J Med Chem,1998, 41: 1112-1123. 被引量:1
  • 10Mylai B L, Carty T J, Moore P F, et al. 1,2-Dihydro-1-oxopyrrolo[3,2,1-kl] phenothiazine-2-carboxamide and Congeners, dual 5-lipoxygenase and cyclooxygenase inhibitors with anti-inflammatory activity. J Med Chem, 1990, 33(7) :2019 -2024. 被引量:1

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