摘要
超分子化学是当今化学界的前沿学科之一,超分子主体化合物的选择性合成是其一个重要的方面。环糊精与冠醚同为超分子化学中应用广泛的主体分子,各有自己独特的特点及不足,而将二者偶联起来,可得到拥有两个甚至多个识别位点的化合物,可通过协同作用在分子识别、模拟酶、色谱等方面拓展其应用范围,并有较好的效果。本文综述了近年来环糊精与冠醚偶联体系的研究进展:首先介绍了不同种类的环糊精与冠醚偶联体系的合成,包括合成思路、步骤以及方法;然后着重叙述了此体系的应用研究进展,包括其在分子识别、模拟酶、异构体分离以及光能量传导等领域;最后指出目前研究工作仍然存在的不足,并对其前景进行了展望。
Supramolecule chemistry is an advanced research topic in current chemistry, and the selective synthesis of the host compound is an important aspect. Cyelodextrins and crownethers, which have their own special characters and disadvantages, are both widely used in supramolecular chemistry. The cyclodextrin-crownether coupling system which has two or more recognition sites will expand their applications greatly in the area of molecular recognition, enzyme mimic, chromatography, etc. through synergistic effection with fine results. Here, the recent development of cyclodextrin- crownether coupling system is reviewed. Firstly, the synthesis of different kinds of cyclodextrin-crownether coupling systems is introduced, including the synthesis clues, approaches and methods. Then, the application of the system is emphatically described, including in the field of molecule recognition, mimetic enzyme, isolation of isomers and energy transfer of light. At last, the disadvantages in recent study and prospects are pointed out.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2009年第12期2515-2524,共10页
Progress in Chemistry
关键词
环糊精
冠醚
偶联体系
模拟酶
分子识别
色谱
cyclodextrin
crownether
coupling system
enzyme mimics
molecular recognition
chromatography
