摘要
目的:评估病理学指标对预测慢性鼻-鼻窦炎伴鼻息肉患者鼻内镜术后疗效的价值。方法:通过对53例接受鼻内镜手术1年以上的慢性鼻-鼻窦炎伴鼻息肉患者的临床症状问卷调查,阅读这些患者的手术标本病理切片,统计相关病理指标,统计学分析慢性鼻-鼻窦炎伴鼻息肉患者接受鼻内镜术后的主要症状及其与病理学指标之间的联系。结果:慢性鼻-鼻窦炎伴鼻息肉患者接受鼻内镜手术后最主要的症状有鼻塞、流脓涕、流清涕或打喷嚏,其中杯状细胞与打喷嚏、流脓涕症状,病理性腺体形成与头昏症状,组织水肿程度与后鼻滴漏症状相关(P<0.05)。结论:病理学指标有助于预测慢性鼻-鼻窦炎伴鼻息肉患者鼻内镜术后疗效。
Objecive：To estimate the predictable value of histopathologic parameters in chronic rhinosinusitis with nasal polyps（CRSwNP） after endoscopic sinus surgery（ESS）. Method： Symptomatology was rated in 53 patients 12 to 24 months after ESS. Specimens taken during the surgical procedure were examined and scored for eosinophils,goblet cells, lymphocytes, subepithelial thickening,subepithelial edema and submucous gland formation. The correlation between histopathologic parameters and postoperative symptoms was then evaluated. Result： The most common symptome after ESS were nasal obsruction, nasal secretion, discharge and sneezing. The correlation between goblet cells and sneezing, discharge, submucous gland formation and headache, subepithelial edema and postnasal secretion was significant（P〈0.05）. Conclusion：Certain histopathologic parameters in CRSwNP are predictive of favorable response to ESS.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2009年第23期1079-1081,1085,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
鼻窦炎
鼻息肉
病理学
疗效
sinusitis
nasal polyps
pathology
curative effect
