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巢白金红杞胶囊对衰老大鼠卵巢的功能提高作用 被引量:1

Effect of Menoprogen on ovarian function of aging rats
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摘要 目的:观察天然药物对衰老卵巢内分泌功能的改善作用。方法:以化学发光法检测15月龄雌性SD大鼠用药前、后血清雌激素(E2)、孕激素(P)、促卵泡生长素(FSH)及促黄体生长素(LH)水平改变;观察比较动物用药前、后的垂体、卵巢、子宫脏器系数变化及组织病理学改变。结果:用药组大鼠血清E2、P水平的提高和血清FSH、LH水平的降低均具有统计学意义;阴道脱落细胞呈现中度雌激素影响;子宫系数明显提高;卵巢内发育卵泡和黄体数量增加,颗粒细胞和卵泡膜细胞明显增殖且排列有序。结论:天然药物巢白金红杞胶囊能改善衰老大鼠卵巢的内分泌功能。 Objective:To observe the effect of natural drug on endocrine function of aging ovary.Methods: With chemiluminescence method,determined the level of estrogen (E2),progestogen (P),follicle stimulating hormone (FSH) and luteinizing hormone (LH) of SD female rats with 15 months age before and after adminisctration. Compared the indexes of pituitary gland,ovary,uterus and pathological status before and after adminisctration. Results: The level of E2 and P increased significantly, while FSH and LH declined significantly in experimental group. E2 had medium effect on vaginal exfoliate cell. The uterus index, follicle and corpus luteum in growth increased obviously. Granular cell and granulosa thecacell increased markedly and had ordered line. Conclusion: Menoprogen capsule can improve the aging ovary in rats.
出处 《海南医学院学报》 CAS 2009年第12期1481-1484,共4页 Journal of Hainan Medical University
基金 海南医学院科研基金资助学报项目(0020090257)~~
关键词 巢白金红杞胶囊 围绝经期综合征 卵巢衰老 激素外治疗法 大鼠 Menoprogen Perimenopause Aging ovary HRT Rat
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