摘要
目的探讨介入在骨和软组织肿瘤临床治疗中的价值。方法对28例经病理证实的骨与软组织肿瘤患者行选择性血管造影、动脉内灌注化疗和(或)栓塞治疗;观察治疗后临床、病理改变。结果动脉灌注化疗和(或)栓塞治疗后23例疼痛缓解或消失;19例软组织消肿,肿瘤缩小;22例在介入治疗后1周内又接受手术治疗并经病理检查,显示瘤细胞不同程度变性、坏死、液化,以并用栓塞治疗者更为显著。肢体肿瘤患者66.4%(10/15)行保肢手术。结论介入治疗是骨与软组织肿瘤的有效治疗方法,值得在临床上推广使用。
Objective To assess the clinical value of interventional treatment for bone and soft-tissue tumors.Methods Selective angiography,transcatheter intra-arterial chemotherapy and / or embolization were performed in 28 patients with pathologically-proved bone and soft-tissue tumors.After treatment the clinical response and pathological changes were observed,and the results were analyzed.Results After transcatheter intra-arterial chemotherapy and / or embolization,relieving or even disappearing of the pain was seen in 23 patients,subside of soft-tissue swelling together with regression of the tumor was seen in 19 patients.Twenty-two patients underwent surgical resection of the lesion one week after interventional treatment.Pathologically,cellular degeneration,necrosis and various degrees of liquefaction were demonstrated on the tumor specimen,which were more obvious in patients treated with embolization.Limp-sparing resection was adopted in 66.7% of patients（10 / 15）.Conclusion Interventional therapy is an effective method for bone and soft-tissue tumors and it is worth popularizing this technique in clinical practice.
出处
《介入放射学杂志》
CSCD
北大核心
2009年第11期865-868,共4页
Journal of Interventional Radiology
关键词
介入治疗
骨与软组织肿瘤
临床分析
interventional therapy
bone and soft-tissue tumor
clinical analysis
