摘要
微小RNA（miRNA）在转录后水平调控基因的表达。研究证实miRNA通过调控细胞的凋亡，在肿瘤的发生发展过程中发挥着重要的作用。肿瘤相关miRNA与凋亡的研究在未来的肿瘤诊疗中miRNA可能具有广阔的应用前景。
MicroRNA, known as micro-RNA or miRNA, is a class of small non-coding RNA whose mature products is - 22 nucleotides long. It negatively regulates gene expression at the post-transcriptional level. More and more studies confirm the important role of miRNA in carcinogenesis and tumor development by regulating cell apoptosis,and the research focuses on tumor-associated miRNA in tumor cell apoptosis may bring widest perspective on treatment and diagnosis of tumor in the future.
出处
《国际肿瘤学杂志》
CAS
2009年第11期803-806,共4页
Journal of International Oncology
基金
国家自然科学基金资助项目（30772231）
教育部新世纪优秀人才支持计划资助（NCET.07.0615）
