摘要
目的分析妊娠期高血压疾病重度子痫前期并发腹水的临床特点和防治方法。方法将184例重度子痫前期患者分为并发腹水组（36例）和未并发腹水组（148例），比较其临床特点。结果重度子痫前期并发腹水组平均终止妊娠时间为（34±4）周，未并发腹水组为（36±3）周，差异有统计学意义（t=2．71，P〈0．01）。重度子痫前期并发腹水组宫内死胎6例（16．67％），新生儿死亡14例（38．89％），早产22例（61．11％）；未并发腹水组宫内死胎4例（2．7％），新生儿死亡16例（10．81％），早产35例（23．65％）；纽间比较差异均有统计学意义（χ2=10．99、16．73、19．01，P均〈0．001）。2组中总蛋白、白蛋白、白／球比值、乳酸脱氢酶、血肌酐、24h尿蛋白差异均有统计学意义[总蛋白：（51．68±6．08）、（59．34±8．28）g／L，白蛋白：（24．32±4．06）、（32．16±5．63）g/L，白／球比值：（0．92±0．26）、（1．16±0．26），乳酸脱氢酶：（495．87±312．56）、（323．81±185．00）U／L，血肌酐：（131．62±95．34）、（91．52±86．83）μmol／L，24h尿蛋白：（4．21±3．51）、（2．38±2．57）g/24h，t=6．17、8．77、5．50、4．79、2．72、3．98，P均〈0．05或〈0．01]。结论重度子痫前期并发腹水病情极为严重，应及时终止妊娠，分娩后腹水可消退；早期、系统、定期的产前检查可及时发现、预防重度子痫前期及并发症的发生。
Objective To analyse clinical characteristics and preventive methods of pregnancy-induced hy- pertensive severe pre-eclampsia with ascites. Methods 184 cases of patients with severe pre-eclampsia complicated with ascite were divided into two groups and the clinical characteristics were compared（ severe pre-eclampsia compli- cated with aseite group,n =36; Severe pre-eclampsia group,n = 148 cases）. Results The average time of the ter- mination of pregnancy was （ 34± 4） weeks in severe pre-eclampsia complicated with ascites group, and （ 36 ± 3 ） weeks in severe pre-eclampsia group （t = 2.71 ,P 〈 0. 01 ）. There were 6 cases of intrauterine stillborn （ 16.67% ）, 14 cases of neonatal mortality （38.89%） ; 22 cases of premature labor （61.11% ） in severe pre-eclampsia complicated with ascites group; There were 4 cases of intrauterine stillborn （2. 7% ）;16 cases of neonatal mortality （10.81%）; and 35 cases of premature labor （23.65%） in severe pre-eclampsia group （χ2 = 10.99,16.73, 19.01 ,P 〈0.001 ）. There were differences in the total protein,albumin,white/ball ratio,lactic acid dehydrogenase, serum creatinine,24-hour urinary protein between the two groups [ total protein：（51.68 ±6.08）g/L vs （59.34 ±8.28） g/L, albumin ： （24.32±4.06 ） g/L vs （ 32. 16 ± 5.63 ） g/L, white/ball ratio ： （ 0.92 ± 0.26 ） vs （ 1. 16 ± 0.26） ,lactic acid dehydrogenase： （495. 87 ± 312. 56） U/L vs （323. 81 ± 185. 00） U /L, serum creatinine： （ 131.62±95.34） μmol/L vs （91.52 ±86.83 ） μmol/L,24 h urinary protein （4.21 ± 3.51 ） g/24 h vs （2.38 ± 2.57）g/24 h,t=6.17,8.77,5.50,4.79,2.72,3.98,P〈0.05 or 〈0.01]. Conclusions The condition of severe pre-eclampsia with ascites is extremely serious, so pregnancy should be timely terminated. The ascites can be dissipated after delivery. Early, systematic and regular prenatal care can prevent severe pre-eclampsia and complications in time.
出处
《中国综合临床》
2009年第12期1317-1319,共3页
Clinical Medicine of China
关键词
重度子痫前期
腹水
妊娠期高血压疾病
预后
Severe pre-eclampsia
Ascites
Hypertensive disorder complicating pregnancy
Prognosis
