摘要
目的观察持续皮下胰岛素输注(胰岛素泵治疗)对重型颅脑损伤高血糖反应和预后影响。方法测定重型颅脑损伤患者入院时的血糖,分成胰岛素泵治疗组(治疗组)和常规胰岛素治疗组(对照组)。观察两组患者在2个月后的疗效。结果重型颅脑损伤后血糖水平显著升高;治疗组患者在胰岛素用量,血糖达到理想控制时间,低血糖发生率低于对照组(P<0.01);治疗组预后与对照组相比差异有显著性(P<0.05)。结论血糖水平是判断颅脑损伤的严重程度和估计患者的预后的重要指标,胰岛素泵治疗是控制严重颅脑外伤后高血糖反应安全有效的措施,可改善患者的预后。
[ Objective ] To observe the effect of continue subcutaneous insulin injection on hyperglycemia and prognosis after severe cranioeerobral injury. [ Methods ] 117 severe craniocerebral injury patients were divided into 2 groups. The level of all patients＇ serum glucose was examined before therapy. The patients of therapy group were given continue subcutaneous insulin injection, the patients of control group were multi-subcutaneous insulin injection. We compared the clinical effect of the two groups after 2 months. [ Results ] The level of serum glucose of severe eraniocerebral injury patients were increased. The level of insulin was given, time of controlling hyperglycemia and frequency of hypoglycemia were decreased in therapy group as compared with that in control group （P 〈0.01）. The outcome of two groups patients were obviously different （P 〈0.05）. [ Conclusion ] The level of serum glucose is a significant indicator on severity head injury, and a reliable predictor of prognosis. Continue subcutaneous insulin Injection is an effective and safe therapy on hyperglycemia after severe craniocerebral injury and make the patients＇ outcome better.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第21期3333-3335,共3页
China Journal of Modern Medicine
关键词
重型颅脑损伤
高血糖
胰岛素泵治疗
预后
severe cranioeerebral injury
hyperglycemia
continue subcutaneous insulin injection
prognosis
