摘要
选择性5-羟色胺再吸收抑制剂如氟西汀、舍曲林、帕罗西汀、氟伏沙明、西酞普兰等常用于治疗各种因素引起的抑郁症,随着使用人数的逐渐增多,所暴露的不良反应也增多。通过检索国外相关文献,发现该类药物暴露其不良反应有时间先后顺序,主要为最早短暂的效应、持续效应、与其他药物或食物相互作用所产生的效应、延迟效应和停药效应。医护人员和患者应警惕该类药物的迟发和停药不良反应,避免使用与其有不良相互作用的其他药物和食物。
Selective serotonin reuptake inhibitors, such as fluoxetin, sertraline, paroxetine and fluvoxamine, are often used to treat depressant disorder caused by various factors. Their adverse reactions after exposure have been gradually become a problem as user populations increased. By reviewing pertinent foreign literatures, we found that the adverse reactions of selective serotonin reuptake inhibitors were exposed according to time sequence. Namely, the reactions include early but transitory effects, lasted effects, effects caused by interacting with food and other medicines, late onset and withdraw effects. The latter adverse reaction caused by selective serotonin reuptake inhibitors should be alerted by nurses and doctors, and food and the other drug interaction should be avoided.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2009年第21期2093-2095,共3页
Chinese Journal of New Drugs
