摘要
目的:研究新生儿窒息后心肌损害的特点及临床意义,提供早期敏感的诊断方法。方法:应用全自动生化分析仪、体表心电图机及彩色超声诊断仪等对30例窒息新生儿的心肌酶、QT离散度及左右心室的收缩和舒张功能进行前瞻性动态观察。结果:新生儿窒息后心肌酶显著增高(P<0.01),QT离散度显著延长(P<0.01);心脏收缩和舒张功能受到严重抑制,其特点是舒张功能首先受累,收缩功能异常则右室重于左室。结论:心肌损伤和心功能障碍是新生儿窒息的常见并发症,QT离散度和超声心动图是评价缺氧缺血性心肌损伤和心功能障碍的特异性指标和敏感方法。
Objective： To study the features and clinical significance of myocardial involvement after birth asphyxia and to offer early and sensitive diagnostic methods. Method：The author prospectively and dynamically observed the variation of myocardial enzymes. QT dispersion （ QTd） and the cardiac function including the systolic and diastolic function of the heart in asphyxiated neonates and healthy controls by using the autobiochemic analyzer, cardiography and color ultrasongraphy. Result： The myocardial enzymes increased remarkably （ P 〈0.01 ） , QTd significandy prolonged （ P 〈0.01 ）. The cardiac dysfunction was observed in neonates after asphyxia. Furthermore, the diastolic dysfunction appeared earlier than the systolic dysfunction did. Conclusion：The myocardial involvement and cardiac dysfunction were the common complication in neonates after birth, asphyxia, QTd and cardiography can be used for specific, sensitive and early methods to evaluate the myocardial involvement and cardiac dysfunction in neonates with birth asohvxia.
出处
《河北医学》
CAS
2009年第12期1413-1416,共4页
Hebei Medicine
关键词
婴儿
新生
窒息
心肌损伤
Infant
Newborn
Asphyxia
Myocardial involvement
