摘要
应用苯那普利治疗原发性高血压患者30例，剂量为3～10mg/d，疗程24周，血压从治疗前24．3／14．4kPa降至18．6／10．5kPa；治疗后的血胰岛素水平、血胰岛素／葡萄糖比值和左心室重量均较治疗前下降（均P＜0．05），提示：苯那普利有明显的改善胰岛素抵抗和左心室肥厚效应。
Thirty patients with essential hypertension were treated with benazepril 3-10 mg daily for 24 weeks. The results showed that there were significant difference(P <0.05) in blood pressure(24. 3/14.4 kPa vs 18. 6/10. 5 kPa),Plasma insulin level,plasma insulin/glucose ratio and left ventricular hypertropy pre-and post-treatment. It suggests that benazepril has a obvious effect on improving insulin resistance and left ventricular hypertropy in patients with essential hypertension.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1998年第6期344-346,共3页
Journal of Clinical Cardiology
关键词
苯那普利
高血压
胰岛素抵抗
左心室肥厚
Benazepril Essential hypertension Insulin resistance Left ventricular hypertropy
