摘要
目的分析早期糖尿病肾病胱抑素C(Cys-c)、免疫球蛋白G(IgG)和D-二聚体(DD)的变化,探讨其在早期糖尿病肾病诊断与治疗中的价值。方法按照Mogensen的DN分型标准对SDM组、EDN组、CDN组和对照组24h尿白蛋白排泄率(urinary albumin excretion rate,UAER)、Cys-C、IgG、DD进行对照,并作相关性分析。结果EDN组和CDN组的Cys-c、IgG和DD与SDM组和对照组比较,差异有统计学意义(P<0.05),EDN组和CDN组的Cys-c、IgG和DD比较,差异有统计学意义(P<0.05)。Cys-c、IgG和DD与UAER的相关系数分别为0.773、0.549和0.385。结论Cys-C、IgG、DD均可作为早期糖尿病肾病的检测指标,以Cys-C的相关性最优。
Objective To evaluate the use of cystatin C（Cys-c）,imunoglobulin G（IgG） and D-dimer（DD） in the early diagnosis and treatment of diabetic nephropathy.Method Mogensen of DN in accordance with sub-standard on the SDM group,EDN group,CDN group and control group in 24 hours urinary albumin excretion rate（UAER）,Cys-C,IgG,DD on the control,and correlation analysis.Results EDN group and the CDN group in Cys-c,IgG and DD with the SDM group and the control group,the difference has statistical significance（P〈0.05）, Cys-c, IgG and DD with UAER the correlation coefficients were 0.773, 0.549 and 0.385. Conclusion Cys-C, IgG and DD can be used as markers in the early diagnosis of diabetic nephropathy. Cys-C had the highest correlation.
出处
《热带医学杂志》
CAS
2009年第10期1164-1165,1175,共3页
Journal of Tropical Medicine
