摘要
目的探讨区域化疗对结直肠癌根治术后患者肝转移的作用。方法治疗组31例大肠癌常规根治术后患者,以介入导管介入法区域化疗替代全身静脉化疗;对照组37例,采用常规静脉化疗;两组化疗方案均为5-Fu+CF+L-OHP,治疗后观察其5年的肝转移发生率及存活率。结果治疗组5年内出现肝转移5例(16.1%)。对照组肝转移12例(32.4%),两组比较有统计学差异(P<0.05)。结论大肠癌常规根治术后患者以介入导管区域化疗替代全身静脉化疗可降低肿瘤肝转移的发生率并提高五年生存率。
Objective To evaluate the effect of catheterization of intraarterial chemotherapy on colorectal cancer, after redieal resection . nothod thirty-one patients undergoing radical resection for their colorectal cancer, given intraarterial regional chemotherapy consisting of 5-FU and L-OHP. The rate of hepatic metastasis were observed. Results the rate of hepatic metastasis from rectal carcinoma was 16.1% .while the rate of control group was 32.4%. Conclusion the intraarterial chemotherapy can reduce the rate of hepatic metastasis from colorectal cancer after redical resection.
出处
《医学信息》
2009年第12期2813-2814,共2页
Journal of Medical Information
关键词
结直肠癌
区域化疗
肝肿瘤/继发性
colorectal cancer
Regional chemotherapy
secondary hepatic carcinoma
