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神经节苷酯对急性脊髓损伤治疗作用的实验研究 被引量:1

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摘要 目的研究神经节苷酯对大鼠急性脊髓损伤后心肌营养素-1表达的影响,探寻神经节苷酯治疗急性脊髓损伤的机制。方法Wistar脊髓损伤大鼠模型随机分为神经节苷酯治疗组、损伤对照组、假手术组,用原位杂交化学和RT-PCR方法检测损伤脊髓心肌营养素-1mRNA的表达。结果脊髓损伤后1、7d神经节苷酯组心肌营养素-1mRNA阳性表达显著高于损伤对照组(P>0.01)。结论神经节苷酯可上调心肌营养素-1mRNA表达,从而促进脊髓损伤后神经再生。
出处 《医学信息》 2009年第12期2759-2760,共2页 Journal of Medical Information
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