摘要
目的提高对盐酸胺碘酮治疗儿童难治性持续性心动过速的认识。方法对2006年1月-2007年12月80例应用盐酸胺碘酮治疗的难治性心动过速患儿的资料进行总结。其中男52例,女38例;年龄1个月～14岁(平均2.5岁)。结果盐酸胺碘酮具有良好的控制心室率的作用,总有效率为90%左右;同时它有不同程度转复窦性心律的作用,房性心动过速67%,阵发性室上性心动过速92%,交界逸搏性心动过速89%、室性心动过速56%;小剂量β受体阻滞剂具有协同盐酸胺碘酮抗心动过速的作用。治疗过程中7例出现低血压,4例出现心动过缓。结论Ⅲ类抗心律失常药盐酸胺碘酮具有广泛的抗心律失常作用,它对治疗血流动力学相对稳定的小儿难治性持续性心动过速是安全有效的。
Objective To improve the understanding of Amiodarone in the treatment of intractable incessant tachycardia in children. Methods Data of 80 patients with intractable incessant tachycardia treated by Amiodarone were summarized. Among them 52 were male, 38 were female, and average age was 2.5 years old. Results Amiodarone reduced heart rate effectively, with about 90% effective. Simultaneously, it could convert tachyeardia into sinus rhythm and succeeded 67% in atrial taehycardia, 92% in paroxysmal supraventricular tachyeardia, 89% in junctional ectopic tachyeardia, 56% in ventricular tachyeardia respectively. Use of small dosage of β-receptor blocker together with Amio- darone showed synergy. Hypotension and bradycardia are the main side effects. Conclusions Too rapid and sustained taehycardia can lead to hemodynamic disorders and cause heart failure, it requires urgent and adequate treatment. Amio- darone can be used to treat different kinds of intractable incessant taehyeardia, and is safe and effective in patients with relatively stable hemodynamis.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2009年第11期1083-1084,1097,共3页
Journal of Clinical Pediatrics
