摘要
Helicoacter pylori are very common patho-genic bacteria colonizing about half of all popula-tions and associated with the development of seti-ous gastroduodenal diseases like gastric lvm-phoma,peptic ulcers and acute chronic gastritis.Current drug regimes are not wholly effective.
Helicobacter pylori are very common pathogenic bacteria colonizing about half of all populations and associated with the development of serious gastroduodenal diseases like gastric lymphoma, peptic ulcers and acute chronic gastritis. Current drug regimes are not wholly effective. Other problems related with the current drug regimes are lack of patient compliance, side effects and bacterial resistance. Thus, drug deliyery to the site of residence in the gastric mucosa may help in solving the problems associated with the current drug therapy. Gastric retentive delivery systems potentially allow increased penetration and thus increased drug concentration at thesite of action.
出处
《中西医结合学报》
CAS
2009年第10期976-982,共7页
Journal of Chinese Integrative Medicine
关键词
幽门螺旋杆菌
胃滞留剂
漂浮剂型
草药
黑柯子
黄连素
Helicobacter pylori
gastroretentive dosage forms
floating dosage forms
herbal drugs
black myrobalan
berberine
