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重组人生长激素联合肠外营养对肝硬化门静脉高压低蛋白血症手术前的应用

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摘要 目的:探讨重组人生长激素(rhGH)联合低热量肠外营养(PN)对肝炎后肝硬化门静脉高压低蛋白血症患者手术前应用的价值。方法:将28例血清白蛋白(Alb,A)含量低于30g/L的患者随机分为观察组及对照组,每组各14例。两组术前均按千克体重给予等热量、等氮的PN治疗及相同的护肝治疗。观察组于术前9d开始皮下注射rhGH4U/d,共9d;对照组给予注射等容量生理盐水。测定两组治疗前和治疗后3、6、9d的各项指标。结果:治疗后6d始观察组血清A较治疗前和对照组均明显升高(P<0.05),且9d时仍维持较高水平(P<0.05)。对照组血清A及两组球蛋白(G)和血糖治疗后无明显变化(P>0.05)。结论:rhGH联合PN支持治疗能改善肝炎后肝硬化门静脉高压低蛋白血症患者的低蛋白状态。
出处 《中国中西医结合外科杂志》 CAS 2009年第5期506-508,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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