摘要
甲基营养菌是一类能够利用一碳化合物作为唯一碳源和能源的微生物,它们在自然界分布广泛。研究表明,甲基营养菌能够直接利用一碳化合物,将其转化成自身代谢的一碳单位,并为生物体提供能源和碳骨架,这组成了一碳代谢的主要部分,它是一种新的代谢体系,可以作为一种新的代谢模式来研究生物代谢和生物进化。本文结合本实验室Methylobacterium sp.MB200的研究情况,主要从分类学、代谢途径、基因组学和应用等方面,论述了甲基营养菌的研究进展。
Methylotrophy is a kind of widespread microbe which can use carbon compound as their only carbon and energy sources. It has been reported that methylotrophy can directly use one carbon compound to transform into their own metabolic one carbon unit, then these one metabolic one carbon units can be used as energy and carbon skeleton by organisms, which is a main part in one carbon metabolism Because this is a novel metabolic system, it can be used in the study of biological metabolism and evolution. Based on the previous study about Methylobacterium sp. MB200 in our lab, here we summarized the research improvements about methylotrophy from their taxonomy, metabolism, genomics and applications.
出处
《微生物学通报》
CAS
CSCD
北大核心
2009年第11期1727-1737,共11页
Microbiology China
基金
广西青年科学基金资助项目(No.0832011)
广西科技攻关项目(No.033002-5)
广西大学科研基金项目(No.X081074)
关键词
甲基营养
甲基杆菌
一碳化合物
一碳代谢
Methylotroph, Methylotrophic bacteria, One carbon compound, One carbon metabolism
