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卫生假说的免疫学机制在哮喘防治中的研究进展 被引量:3

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摘要 哮喘的特征是慢性气道炎症和气道高反应性。目前对哮喘治疗的认识是"可以控制,但不能治愈"。近年来,哮喘发病的"卫生假说"提出早期微生物的暴露可能对哮喘的发病起保护作用。传统的解释是微生物负荷增加可诱导免疫反应向Th1偏移。由于哮喘是由免疫耐受缺陷导致的疾病,因此诱导抗原特异性T细胞耐受可能是此假说的另一种解释,并有望因此为防治哮喘提供新的思路。
出处 《中华哮喘杂志(电子版)》 CAS 2007年第1期57-60,共4页 Chinese Journal of Asthma(Electronic Version)
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