摘要
目的探讨乳腺癌前哨淋巴结活检术(sentinellymph node biopsy,SLNB)的放射安全性。方法采用热释光剂量计(thermoluminescent dosimeters,TLD)检测在SLNB过程中患者乳房注射部位、胸腺、盆腔性腺及医务人员优势手食指、胸腺、盆腔性腺、眼晶体接受的放射线剂量。2006年10月至2007年7月连续检测行乳腺单纯切除/保留乳房+SLNB的乳腺癌患者40例。结果患者乳房注射部位的吸收剂量最大(5.946±5.023)mSv,显著高于胸腺及盆腔的吸收剂量(均P=0.000)。主刀医师、第一助手、器械护士各部位核素吸收剂量差异无统计学意义(均P>0.05),远远低于我国卫生部确定的放射卫生防护基本标准。依据该标准,术者每年完成约1000台SLNB手术在放射安全性方面是安全的。结论核素法SLNB对患者和医务人员是安全的,不需要进行防护。
Objective To study the radiologic safety of sentinel lymph node biopsy （SLNB） in breast cancer. Methods SLN was detected with methyhhionium and ^99Tc^m-sulfur colloid. Thermoluminescent dosimeters （TLD） were used to detect radiation dose received by medical stuff and 40 cases treated with breast conserving surgery or mastectomy and SLNB between October 2006 and July 2007. The TLDs were set at the breast injection site, thoracic gland, and cavitas pelvis gonad of patients, and dominant hand index finger, thoracic gland, eavitas pelvis gonad and ocular lens of medical stuffs. Results The mean radiation dose received at the breast injection site （5. 946 ± 5. 023 mSv） was significantly higher than that at the thoracic gland and cavitas pelvis gonad of the patients （ both P = 0. 000）, The mean radiation dose received at different parts of different medical stuff had no statistical significance （ all P 〉 0.05 ） , which was far lower than basic criterion of radiological health protection from the Department of Health of China. According to this criterion, it would be safe for surgeons to perform 1000 cases of SLNBs annually. Conclusions SLNB in breast cancer is radiological safe both for patients and medical stuffs, and no radiologic protection is necessary during operation.
出处
《中华乳腺病杂志（电子版）》
CAS
2007年第6期214-219,共6页
Chinese Journal of Breast Disease(Electronic Edition)
关键词
乳腺癌
前哨淋巴结活检
热释光剂量计
放射安全性
Breast neoplasms
Sentinel lymph node biopsy
Thermolnminescent dosimeter
Radiology safety
