摘要
目的探讨非妊娠性绒毛膜上皮癌的相关临床问题。方法分析2例不同来源的男性绒癌患者的临床和手术后随访资料。结果2例患者均在术后经病理确诊为绒癌,查血β-HCG均有不同程度升高。1例病情迅速恶化死亡;1例在术后接受了进一步放疗,随访半年情况良好。结论非妊娠性绒癌是少见的高度恶性肿瘤,常急性起病,临床表现多变,术前诊断较为困难,HCG对疾病的诊断和观察有重要作用。
Objective The goal of this study was to elucidate the clinical problems of the non-gestational choriocarcinoma. Methods Two cases of intracranial male choriocarcinoma with different primary sites were reported and analysed on their clinical and postoperative follow-up data. Results These two patients were diagnosed as having a choriocarcinoma and their serum β-HCG were elevated. One patient died before appropriate therapy could be instituted. The other patient received surgical operation followed by radiotherapy. Six months after surgery, the patient remained improved. Conclusions Non-gestational choriocarcinomas are rare and malignant and their symptoms are very acute in the onset. The diagnosis of non-gestational choriocarcinomas are difficult before operation due to a highly variable clinical presentation. The serum β-HCG concentration has an important role in diagnosis and monitor of clinical progress.
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2009年第10期598-601,共4页
Chinese Journal of Nervous and Mental Diseases
关键词
非妊娠性绒癌
人绒毛膜促性腺生长激素
诊断
Non-gestational choriocarcinoma Human chorionic gonadotropin Diagnosis
