摘要
目的应用定量组织速度成像(QTVI)和应变率成像(SRI)技术对慢性阻塞性肺疾病(COPD)患者右心室功能进行检测,旨在探讨两种技术评价COPD患者右心室功能可行性。方法COPD患者38例(男性25例,女性13例,年龄55～71岁,平均年龄62岁)、对照组50例(男性33例,女性17例,年龄48～72岁,平均年龄62岁),获取心尖四腔TVI图像,测量收缩期峰值运动速度(Vs)、舒张早期峰值应变率(Ve)、收缩期峰值应变率(SRs)、舒张早期峰值应变率(SRe)。结果根据肺动脉压将COPD患者分为肺动脉高压(PAH)组和无肺动脉高压(NPAH)组;与对照组比较,PAH组和NPAH组右心室游离壁和室间隔Vs、Ve、SRs、SRe均显著减低,三尖瓣环Vs、Ve均显著减低;与NPAH组比较,PAH组右心室游离壁和室间隔Vs、Ve、SRs、SRe均显著降低,三尖瓣环Vs、Ve差异无统计学意义。结论COPD患者无论有无肺动脉压增高,其右心室局部与整体功能已经受损,但在肺动脉压增高患者右心室功能受损更重;QTVI与SRI技术可有效评价COPD患者右心室功能。
Objective To evaluate right ventricular function in patients with chronic obstructive pulmonary disease（COPD）by quantitative tissue velocity imaging（QTVI）and strain rate imaging（SRI）.Methods Echocardiography were performed in 38 patients with COPD（male 25,female 13,aged 55-71 years,mean age 62 years）and 50 controls（male 33,female 17,aged 48-72 years,mean age 62 years）.The TVI of apical four chamber views were adopted.The indices included：peak systolic velocity（Vs）,peak early diastolic velocity（Ve）,peak systolic strain rate（SRs）and peak early diastolic strain rate（SRe）.Results According the pulmonary arterial pressure,the patients with COPD were divided into pulmonary arterial hypertension（PAH）group and non-pulmonary arterial hypertension（NPAH）group.Compared with controls,the Vs,Ve,SRs and SRe of right ventricular free wall and interventricular septal in PAH group and NPAH group decreased significantly,while Vs,Ve of tricuspid annulus decreased significantly.Compared with NPAH group,the Vs,Ve,SRs and SRe of right ventricular free wall and interventricular septal in PAH group decreased significantly,but there was no significant difference in Vs,Ve of tricuspid annulus between 2 groups.Conclusion Function of right ventricle in patients with COPD has been damaged whether there is PAH or not,but the damages are more significant in PAH patients.It is demonstrated that the technique of QTVI and SRI could effectively evaluate the right ventricular function in COPD patients.
出处
《生物医学工程与临床》
CAS
2009年第5期439-441,F0002,共4页
Biomedical Engineering and Clinical Medicine
关键词
定量组织速度成像
应变率成像
慢性阻塞性肺疾病
右心室功能
quantitative tissue velocity imaging
strain rate imaging
chronic obstructive pulmonary disease
right ventricular function
