摘要
目的:探讨了男性不育症患者血清IL-6、T、LH、FSH和PRL水平的变化及临床意义。方法:应用放射免疫分析对68例男性不育症患者进行了血清IL-6、T、LH、FSH和PRL检测,并与35名男性正常人作比较。结果:男性不育症患者血清T水平非常显著地低于男性正常人组(P<0.01),而IL-6、FSH、LH和PRL水平又非常显著地高于男性正常人组(P<0.01)。血清IL-6水平与T水平呈负相关(r=-0.4186,P<0.01,与FSH、LH和PRL水平呈正相关(r=0.6018、0.5912、0.6214,P<0.01)。结论:检测男性不育症患者血清IL-6、T、LH、FSH和PRL水平的变化对诊断、预后判断及治疗均有较大的实用价值。
Objective To explore the significance of changes of serum IL-6,T,LH,FSH,PRL levels in male patients with infertility.Methods Serum IL-6,T,LH,FSH,PRL（with RIA） were measured in 68 male patients with infertility and 35 controls.Results Serum T levels were significantly lower in the patients than those in controls（P〈0.01）,while the serum IL-6,FSH,LH,PRL levels were significantly higher in the patients（P〈0.01）.Serum IL-6 levels were negatively correlated with T levels in the patients（r=-0.4186,P〈0.01）,and positively correlated with FSH,LH and PRL levels（r=0.6018,0.5912,0.6214,P〈0.01）.Conclusion Serum IL-6,T,LH,FSH,PRL levels were significantly changes in male patients with infertility and determination of which might be infertility and of prognostic importance.
出处
《放射免疫学杂志》
CAS
2009年第5期467-469,共3页
Journal of Radioimmanology
关键词
男性不育症
白细胞介素-6
睾酮
促黄体生成素
促卵泡激素
垂体泌乳素
male infertility
interleukin-6（IL-6）
testosterone（T）
luteinizing hormone（LH）
follicle stimulating hormone（FSH）
prolactin（PRL）
