摘要
目的:研究扁桃体摘除治疗IgA肾病的适应证、临床效果及安全性。方法:将207例经肾活检确诊为IgA肾病患者分为手术组及对照组,手术组患者术后治疗方案与对照组相同,随访时间为1年,观察两组病例的蛋白尿水平、红细胞数量及血压、肾功能情况变化。结果:手术组3个月后尿红细胞数量、尿蛋白定量明显好于对照组,手术组血压、内生肌酐清除率及对照组血压无明显变化,但对照组内生肌酐清除率则出现下降。结论:扁桃体摘除治疗合并慢性扁桃体炎的IgA肾病临床疗效肯定,对肾功能有保护作用。
Objective：To investigaten the clinical efficacy and safety of tonsil removal in patients with IgA nephropathy. Methods：A total of 207 nephropathy patients diagnosed by renal biopsy in our hospital were randomly assigned into surgical group or control group,all patients were followed for one year,The changes of the proteinuria level,RBC count, blood pressure（BP） and renal funtion were observed. Resrults： After three months, the urine RBC, quantitative proteinuria of the surgical group were significantly better than those of the control group; BP and creatinine clearance rate（Cer）of the surgery group, BP of the control group,were no significant changes, but for the control group, Ccr was decreased. Conclusion： Tonsillectomy in IgA nephropathy combined with chronic tonsillitis played an important role in protecting the renal function.
出处
《中国临床医学》
2009年第5期794-795,共2页
Chinese Journal of Clinical Medicine
