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SDF-1/CXCR4轴在肝脏干细胞移植中的应用 被引量：7

Stromal cell-derived factor-1/CXC chemokine receptor-4 axis and hepatic stem cell transplantation
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摘要 基质细胞衍生因子-1(stromal cell-derived factor-1,SDF-1)及其受体CXCR4构成SDF-1/CXCR4轴体系统.近年来随着该领域科研的不断深入,越来越多的研究发现SDF-1/CXCR4轴体系统在组织损伤及修复中起着重要的作用.本文主要对SDF-1/CXCR4轴体系统的生物学特性及其在肝脏干细胞移植中的作用进行综述. The stromal cell-derived factor-1 （SDF-1）/CXC chemokine receptor-4 （CXCR4） axis consists of SDF-1 and its receptor CXCR4. In recent years, more and more studies suggest that the SDF-1/ CXCR4 axis plays an important role in tissue repair after injury. In this review, we will focus on the biological characteristics of the SDF-1/ CXCR4 axis and its relationship with hepatic stem cell transplantation.
作者 高福来 韩明子 金世柱 胡宗晶
机构地区 哈尔滨医科大学附属二院消化内科 吉林大学第一医院胃肠内科
出处 《世界华人消化杂志》 CAS 北大核心 2009年第24期2474-2477,共4页 World Chinese Journal of Digestology
关键词 基质细胞衍生因子 干细胞 SDF-1/CXCR4轴体系统 生物学特性 Stromal cell-derived factor-i Stem cell SDF-1/CXCR4 axis Biological characteristics
分类号 R575 [医药卫生—消化系统]
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参考文献28

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二级参考文献67

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共引文献14

同被引文献88

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引证文献7

二级引证文献20

世界华人消化杂志
2009年 第24期

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