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延迟PCI对急性心肌梗死患者血浆脑钠肽N末端前体的影响

The effect of delayed PCI on NT-proBNP in patients with acute myocardial infarction
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摘要 目的探讨延迟PCI对AMI患者心功能的影响。方法选择在本院住院治疗的AMI患者97例,根据是否行延迟PCI术分为两组(PCI组和非PCI组),两组患者均于入院即刻、心梗后7天左右、6个月左右检测血浆中脑钠肽N末端前体(NT-proBNP)水平的变化;分别于AMI后两周、心梗后6个月左右做心脏超声检查,测定患者左室射血分数(EF)和左室舒张末期容积(EDV)。对比PCI组和非PCI组两组患者心脏超声和NT-proBNP的动态变化。结果6个月后PCI组的NT-proBNP较非PCI组低(P<0.01);PCI组的EF值明显高于非PCI组(P<0.05),非PCI组左室舒张末期容积(EDV)明显大于PCI组(P<0.05)。结论延迟PCI能改善AMI患者的心功能。 Objective To evaluate the efficacy of delayed PCI on heart faction in patients with acute myocardial infarction. Methods 97 patients with AMI were divided into treatment group and control group. Based on PCI -group and non-PCI group, the plasma BNP leavel were measured in these patients immediately and 7 clays, 6 months after AMI Left ventrieular volume index ,ejection fraction and left ventrieular end diastolic end volume indexes were measured in 2 weeks and 6 months in each group after AMI, Results 6 months after AMI,BNP in the PCI group singnificant lower than the non-PCI group, left ventrieular end diastolic volume in non-PCI group were singnifieant larger than the PCI group. Conclusion Delayed PCI for infact-related artery would inhibit ventricular enlargement henefit to the heart faction.
出处 《中国现代医药杂志》 2009年第10期36-38,共3页 Modern Medicine Journal of China
关键词 延迟PCI NT—proBNP 心功能 Delayed PCI N-teminal pro-brain natriuretic pepeide Heart function
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