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白假丝酵母菌对吡咯类药物耐药机制研究进展

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摘要 白假丝酵母菌对吡咯类药物产生耐药已成为临床长期用药治疗的一个突出性问题,目前认为白假丝酵母菌耐药性产生的机制,主要包括麦角甾醇生物合成通路中关键靶酶的变异或高表达、受基因调控的药物外排泵蛋白表达的变化以及生物被膜的形成等。
作者 李春 王中新
出处 《国际检验医学杂志》 CAS 2009年第10期981-983,共3页 International Journal of Laboratory Medicine
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参考文献15

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