摘要
目的对栽培于辽宁本溪的曼地亚红豆杉(Taxus media‘Hicksii’)针叶的化学成分进行研究。方法曼地亚红豆杉针叶的乙醇提取物经大孔树脂、硅胶柱色谱、ODS柱色谱、凝胶柱色谱进行分离纯化,依据1H-NMR、13C-NMR、ESI-MS、HRESI-MS鉴定其结构。结果从曼地亚红豆杉针叶的乙醇提取物中分离纯化得到6个化合物,分别鉴定为二萜类化合物:5-cinnamoyl-9-acetyltaxicin-I(1)、5-cinnamoyl-10-acetyltaxicin-I(2)、5-去桂皮酰基紫杉宁J(3)、紫杉醇(4);黄酮类化合物:柚皮素(5);脂肪酸类:十六烷酸(6)。结论化合物1、2、5和6为首次从曼地亚红豆杉中分离得到。
Objective To investigate chemical constituents from the needles of Taxus media growing in Liaoning province of China. Methods The needles of the plant were extracted with ethanol;the ethanol extract was submitted to chromatography on silica gel column, ODS and Sephadex LH-20 for the isolation. Their structures were elucidated on the basis of spectral analysis. Results Six compounds were isolated and identified as 5-cinnamoyl-9-acetyltaxicin-I （ 1 ）, 5-cinnamoyl-10-acetyltaxicin-I （ 2 ）, 5-decinnamoyltaxinine J （3）, taxol （4）, nadngenin （ 5 ）, hexadecanoic acid （ 6 ）. Conclusions Compounds 1,2,5 and 6 are isolated from Taxus media‘Hicksii＇.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2009年第10期789-791,799,共4页
Journal of Shenyang Pharmaceutical University
关键词
曼地亚红豆杉
紫杉烷二萜
黄酮
脂肪酸
化学成分
结构鉴定
Taxus media＇Hicksii＇
taxane diterpene
flavonoid
fatty acid
chemical constituent
structure identification
