摘要
目的:建立六味地黄片的质量标准。方法:用薄层色谱(TLC)法对方中熟地黄、泽泻进行定性鉴别;用高效液相色谱法测定山茱萸中马钱苷的含量及牡丹皮中丹皮酚的含量。结果:熟地黄、泽泻的TLC斑点清晰,分离度好。马钱苷、丹皮酚的检测浓度分别在5.77～115.40μg.mL-1(r=0.9999)、5.12～102.50μg.mL-1(r=0.9998)范围内与各自峰面积积分值呈良好的线性关系;平均回收率分别为98.4%、97.08%,RSD分别为0.75%、1.07%(n均=6)。结论:所建标准可用于六味地黄片的质量控制。
OBJECTIVE： To establish the quality standard of Liuwei dihuang tablets. METHODS： The ingredients such as Radix Rehmanniae Praeparata and Alisma orientalis were identified by TLC, and the content of loganin in Cornus officinalis and the content of paeonol in Paeonia suffruticosa were determined by HPLC. RESULTS： The TLC spots of Radix Rehmanniae Praeparata and Alisma orientalis were distinctive and well - seperated. The linear ranges of loganin and paeonol were 5.77--115.40 μg·mL^-1（ r = 0.999 9） and 5.12-- 102.50μg·mL^-1（ r = 0.999 8）, respectively, and their average recovery rates were 98.4% （RSD = 0.75% ） and 97.08% （RSD = 1.07% ）, respectively（ n = 6 each） . CONCLUSION： The established standard is applicable for the quality control of Liuwei dihuang tablets.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第30期2376-2378,共3页
China Pharmacy
