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妊娠急性脂肪肝8例临床分析

Clinical analysis of 8 patients with acute fatty liver of pregnancy.
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摘要 目的探讨妊娠急性脂肪肝的临床诊断及治疗方法,降低孕产妇及围生儿的病死率。方法对我院1998年1月~2007年7月收治的8例妊娠急性脂肪肝患者的临床资料进行回顾性分析。结果8例患者为初产妇、发病孕周为28~37周,单胎3例,双胎4例,三胎1例。5例阴道分娩,2例剖宫产,1例产后转入,经积极的支持治疗,孕产妇6例存活,2例死亡。共计14个围生儿7例存活,7例死亡,病死率50%。结论对于AFLP患者明确诊断、立即终止妊娠、积极内科综合支持疗法是改善母儿预后的关键。 Objective To study the clinical diagnosis and treatment of acute fatty liver of pregnancy(AFLP).Methods The clinical data of 8 cases of AFLP were reviewed retrospectively,who were treated during Jan 1998 to Dec 2007 in the Department of obstetrics and cynecology,second people′s hospital of Lianyungang.Results Eight cases of AFLP were primiparas.The gestational age at onset was 32~36 weeks.Two cases of AFLP were single birth and six cases were twins.The survival puerperas of AFLP were 6 cases in all and the mortality of puerperas were 40 percent.Seven neonates were dead and the mortality of neonates were 50 percent.Conclusion Early diagnosis,termination of pregnancy as soon as possible and a comprehensive therapy are the key to improve the survival of mother and newborn.
出处 《四川医学》 CAS 2009年第9期1407-1409,共3页 Sichuan Medical Journal
关键词 妊娠 妊娠急性脂肪肝 pregnancy acute fatty liver of pregnancy
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