摘要
目的：研究克痫散对小白鼠全身性持续性惊厥的影响。方法：５６只小白鼠随机分为生理盐水，克痫散，安定和苯巴比妥组。以上四组动物每天用上述四种制剂灌胃一次，连续灌胃３０天后，每只小白鼠腹腔注射盐酸氨基脲２００ｍｇ／ｋｇ，诱发癫痫，记录出惊厥持续时间和死亡情况，进行统计学处理。结果：克痫散组的全身性惊厥较其他组轻微，惊厥持续时间较短。
Objective:To study the effect of Kexian powder on continuous genendized convulsion of the mice. Method: 56 mice were randomly divided into saline group, Kexian powder group, valium group and barbiturates group. The drugs mentioned above were administered orally everyday. And then 30 days later, each mice was injected with 200mg/kg semicarbazide hydrochloride into the abdomen to induce epilepsy. The durations of convulsion and death rate and time were meorded and analized statistically. Results:The generalized convulsion in Kexian powder group was milder and the duration was shorter. The death rate was lower and the death time delayed (P < 0.01 ). Couclusion: Kexian powder provided by Chuanying hospital of the traditional Chinese medicine has significant effect on continuous generalized convulsion induced by semicarbaxide.
关键词
癫痫
克痫散
全身性
持续性
惊厥
epilepsy, Kexianpowder
continuous generalized convulsion
