摘要
目的:研究盐酸氨溴索对喘息小儿肺功能的影响。方法:应用潮气呼吸流速容量环(TBFV环)对喘息性疾病患儿进行盐酸氨溴索雾化吸入前后肺功能各项指标进行测定。结果:反映通气功能的Vi/kg、反映小气道功能中的PTEF、反映大气道功能的ME/MI雾化前后差异均有统计学意义(P<0.05),而反映小气道功能中的%V-PF、25/PF、反映通气功能的RR雾化前后差异无统计学意义(P>0.05)。结论:盐酸氨溴索仅有部分的支气管扩张作用,并且很大程度上依赖于其祛痰作用。
Objective： To study the effect of ambroxol as a bronehodilator on infants with wheezing disease. Methods： Several indexes of lung function test pre- and post-inhalation of ambmxol atomization were compared in 45 cases by tidal breath flow volume loop （ TBFV loop）. Results： There were significant differences in Vi/kg related to the ventilation function, FIEF related to the small airway function and MEMI related to the big airway function （ P 〈 0.05）. But % V-PF and 25/PF which were also related to the small airway function and RR to the ventilation function, showed no significant difference （ P 〉 0.05）. Conclusions： Ambroxol is only effective as bronehodilator to certain degree, and its effect relies heavily on the role of being expectorant.
出处
《儿科药学杂志》
CAS
2009年第5期17-19,共3页
Journal of Pediatric Pharmacy
