摘要
目的:建立首当颗粒剂的质量控制方法.方法:用薄层层析法对其中的炒当归、补骨酯和陈皮进行定性鉴别,用高效液相色谱法对其中的指标成分大黄素进行了定量测定.紫外检测波长为λ436nm.结果:线性范围0.02～0.2μg,平均回收率为101.1%(n=5),RSD为1.20%.结论:鉴别和含量测定方法中各阴性对照品均无干扰,含量测定方法灵敏度高,重现性好,可作为该制剂的质量控制标准.
OBJECTIVE: A quality control method was established for Shoudang granules. METHODS: Its ingrediets angelica sinensis diels, psoralen and citrus reticulata bianco were identified by TLC. A HPLC method for determing emodin, the mark ingredients in the granules,was established.Detective wavelength was 436nm.RESULTS:The method was linear within the range of 0.02 - 0.2μg,the average recovery was 101.1%,and the USD was 1.20% . CONCLUSION:The method is sensitive and highly reproducible,and may be used for the quantitative determination of the granules.
出处
《中国现代应用药学》
CAS
CSCD
1998年第5期41-44,共4页
Chinese Journal of Modern Applied Pharmacy
关键词
首当颗粒剂
薄层色谱
高效液相色谱
质量标准
Shoudang Granules,TLC,HPLC,polgonum multiflorum,angelica sinensis diels,emodin
