摘要
苯并杂类化合物为常用镇静剂及治疗心血管疾病和抗病毒的药物［１～３］，苯并杂与五六元杂环并合形成的三环化合物也是重要的药用杂环化合物，如１，４－苯并二氮杂与１，２，４－三唑并合形成的三环化合物为常用的治疗中枢神经系统疾病药物［４］．而吖丙啶与１，...
Title compound was synthesized by insertion and cycloaddition reaction of 2,4 diphenyl 2,3 dihydro 1,5 benzothiazepine and dichlorocarbene generated from chloroform under the alkaline condition and its crystal structure was determined by X ray diffraction method. The single crystals belong to orthogonal, space group Pc2 1 /n with a = 1.024 3(2) nm, b = 1.145 1(2) nm, c = 1.838 8(3) nm, V = 2. 157 0(5) nm 3, Z =4, D c=1.693 g·cm -3 , μ =0.066 mm -1 , F (000)= 1 066 for 2 467 reflections, R =0.039, R w=0.054.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1998年第11期1774-1776,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
四氢
吖丙啶并
苯并硫氮杂辛因
苯并杂Zhuo
合成
a
2
3
4 Tetrahydro
1H
azirinobenzothiazocine
Crystal structure
Molecular structure
