摘要
随着生活水平的提高、饮食习惯的改变以及糖尿病和代谢综合征患病率的急速上升,非酒精性脂肪性肝病的发病率不断的升高.最近的研究表明此病与胰岛素介导的磷脂酰肌醇3-激酶(phosphatidylinositol 3-kinase,PI-3K)传导通路有着密切的关系,他在非酒精性脂肪性肝病发病机制中起着关键的作.本文就PI-3K在非酒精性脂肪性肝病中的作用机制研究现状作一综述.
Due to improvement in living standards, changes in eating habits, as well as a sharp increase in the incidence of diabetes and metabolic syndrome, the incidence of nonalcoholic fatty liver disease is continuously increasing. Recent studies have shown that the phosphatidylinositol 3-kinase （PI-3K） pathway plays a crucial role in the pathogenesis of nonalcoholic fatty liver disease. In this article, we will review the role of PI-3K in the pathogenesis of nonalcoholic fatty liver disease.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第22期2277-2282,共6页
World Chinese Journal of Digestology
